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AIOct 20, 2026 · 1:21 AM ET · Latent Space

Congrats to DeepSeek V4.1 Flash 1017, MiniMax M3.1 Flash, and Mercury 3 (details below) but they’re not going to be in super wide use just yet.

Builder score 33Why it scoresRules judge: AI item; Source: Latent Space.
AIOct 19, 2026 · 8:00 PM ET · OpenAI News

OpenAI is acquiring Orchestra Bio to bring AI-powered operations to life sciences R&D, helping biopharma teams accelerate drug development and advance new treatments.

Builder score 33Why it scoresRules judge: AI item; Source: OpenAI News.
AIOct 19, 2026 · 7:58 PM ET · Simon Willison

My obituary for programming Jeremy Scheff poignantly captures the key loss caused by coding agents for career programmers who enjoyed the puzzle of developing code: Programming turned into one of the greatest jobs you could imagine. You got paid to work on tricky little logic puzzles. The trickier the puzzle, the more you got paid. But even pretty simple puzzles were worth a lot of money because...

Builder score 67Why it scoresRules judge: AI item; Topics: agents, labor share; Source: Simon Willison.
AIOct 19, 2026 · 8:00 AM ET · OpenAI News

Learn how OpenAI is improving ChatGPT across low-resource programming languages, with new evaluations for software engineering, SQLite, and COBOL migration.

Builder score 33Why it scoresRules judge: AI item; Source: OpenAI News.
CapitalOct 19, 2026 · 6:00 AM ET · Stratechery (free posts)

Apple has a lot of trust in terms of delivering integrated products and preserving privacy; the real trust question is if you think Siri AI will justify investing more in their ecosystem.

Builder score 33Why it scoresRules judge: Capital item; Source: Stratechery (free posts).
AIOct 18, 2026 · 7:43 PM ET · Simon Willison

Release: llm-tools-datasette 0.1.1 When I switched LLM over to httpx2 in LLM 0.33 I forget that this would break any plugins which used httpx without directly depending on it. llm-tools-datasette was one of those plugins, now fixed. Tags: datasette , llm

Builder score 33Why it scoresRules judge: AI item; Source: Simon Willison.
AIOct 18, 2026 · 7:16 PM ET · Simon Willison

Release: llm-echo 0.5 I'm working towards a new LLM release, and testing PRs caused me to revisit the llm-echo debug plugin. This plugin provides a "model" which doesn't involve an LLM at all - it just repeats back the prompts that have been fed to it. The new release now updates the simulated token usage counts to take tool calls, system prompts, and reasoning tokens into account. Example usage...

Builder score 33Why it scoresRules judge: AI item; Source: Simon Willison.
AIOct 17, 2026 · 5:11 PM ET · Simon Willison

Inline rendering with document​.currentScript Lean Rada describes a neat trick that takes advantage of the document.currentScript property. You can use that to drop in a tiny inline If you define a shortcut function like this: $=(...n)=>document.currentScript.replaceWith(...n) You get a tiny template language: The year is Tags: javascript

Builder score 50Why it scoresRules judge: AI item; Topics: real estate; Source: Simon Willison.
AIOct 17, 2026 · 9:16 AM ET · Simon Willison

Release: web-edit 0.1a2 web-edit ( previously ) is my tiny web app for browsing and editing files in a folder. I mainly built it for editing files on different machines via Tailscale. I added a "copy to clipboard" option for both text and image data. I needed this because I was running pelican prompts on a laptop from my phone (here's DeepSeek 4.1 Flash 1017 ) and I wanted an easy way to copy the...

Builder score 33Why it scoresRules judge: AI item; Source: Simon Willison.
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